Product Name :
OGG1 Recombinant Rabbit Monoclonal Antibody [JA18-13]
Predicted band size :
39 kDa
Observed band size :
39 kDa
Synonyms:
8 hydroxyguanine DNA glycosylase antibody 8 oxoguanine DNA glycosylase 1 antibody 8 oxoguanine DNA glycosylase antibody AP lyase antibody DNA (apurinic or apyrimidinic site) lyase antibody DNA apurinic or apyrimidinic site lyase antibody DNA lyase antibody DNA-(apurinic or apyrimidinic site) lyase antibody HMMH antibody HOGG 1 antibody 展开
Function :
DNA repair enzyme that incises DNA at 8-oxoG residues. Excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine (FAPY) from damaged DNA. Has a beta-lyase activity that nicks DNA 3′ to the lesion. The OGG1 gene encodes 8 isoforms (OGG1A-C, OGG2A-E) which result from alternative splicing of a single messenger RNA. The OGG1A splice variant is the most prevalent form and localizes to the nucleus, whereas the OGG2A splice variant is targeted to the mitochondria.
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Synthetic peptide within Human OGG1 aa 296-345 / 345.1411774-27-0 uses
Species reactivity:
Human
Verify application:
WB, IHC-P
Coupling :
unconjugated
Clone number:
JA18-13
RRID:
AB_3070522
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.Potassium trichloroammineplatinate(II) Formula Aliquot store at -20℃ or -80℃.PMID:33500210 Avoid repeated freeze / thaw cycles.
Storage buffer solution:
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
39 kDa
Positive control :
Human kidney tissue, Daudi cell lysates.